Neurocosmetic Hexapeptide 389A – A bioactive peptide designed to act like a topical neuromodulator, targeting muscle tension and smoothing forehead lines without injections.
Botanical polysaccharides & skin-penetrating agents – Enhance delivery via nanotransport to deeper dermal layers.
Hydration matrix – includes hyaluronic acid to moisturize while patch is worn.
These are embedded in an easy-to-apply, needle-free, nanotechnology-enhanced patch specifically for the forehead (and optionally upper lip / procerus area. The formula is FDA-registered, with boutique, small-batch production.
📝 Usage Instructions
Based on product info and typical protocols:
Cleanse thoroughly and dry the forehead.
Apply patch (adhesive side down) over forehead lines; optional placement on upper lip or glabellar region.
Wear duration: around 4–10 days per patch—minimum visible improvement after 4 days; full 10-day cycle recommended.
Repeat cycles as needed, up to ~30 days, then pause—mirrors injectable-like schedule.
⏳ Expected Effects & Timeline
Within ~4 days: Noticeable softening of dynamic and static lines.
After 10 days: Substantial smoothing and plumping effects, reported in brand marketing to last a month.
Mechanism: Peptide acts to partially inhibit neurotransmitter release (similar to Botox but milder), plus hydration and dermal delivery enhance texture.
🔬 Research & Scientific Background
Acetyl hexapeptides (e.g., Argireline/AHP‑8 / hexapeptide‑3/8) have been shown to inhibit neurotransmitter release and mimic botox-like neuromodulation
In vitro/human trials, topical Argireline improved wrinkle depth ~20–30% after 30 days, with no adverse effects,
Transdermal peptide delivery technology (e.g., microneedle/ionic liquid enhancers) significantly boosts skin penetration and retention—some systems up to ~5–7× over standard methods
Neurocosmetic review supports the idea of topical neuromodulators applied to the skin-nervous system interface to reduce stress-related skin aging.
Although no independent clinical trial exists specifically for Hexapeptide 389 patches, the formulation builds upon well-studied acetyl hexapeptides and advanced transdermal delivery technology mimicking neuromodulator effects.
⚠️ Safety & Considerations
Generally well tolerated and designed for prolonged wear (days).
Patch-based format reduces risk of irritation seen with needles or injections.
Side effects like redness or discomfort are rare but patch-test recommended.
Always remove and replace according to suggested cycle to prevent over-treatment.
✅ Summary Table
Aspect
Details
Form
Adhesive forehead patch with nanotransport delivery
Key Active
Hexapeptide 389A (neuromodulator-like)
Supporting matrix
Polysaccharides & hydration enhancers
Wear Time
~4–10 days per patch; visible effect in ~4 days
Treatment Cycle
10 days on, then pause; can repeat cycles matching injectable Botox pacing
